I can't say I'm surprised that the show has been canceled/ended. I'm glad it was decided early enough so that the writers could give the show a proper ending.
The show was really great up until the last two seasons where it just got boring. For me it was the whole "Huddy" thing which really made no sense, (I've always been a House/Cameron shipper), and the lack of Thirteen who made the show more interesting and fun. This season started off great with two new characters, but quickly became boring again.
I have to admit that I'm curious about how the writers plan to end the show. I can only imagine one thing that would make the ending perfect, (I really hope no fans come after me with pitchforks for saying this), House dying. Think about it. How else could the show end? He's already been in rehab twice, he spent a year jail, he's fired his team, so the only thing that hasn't been done yet is killing him off, and who knows, maybe Thirteen can come along and help him end his life if he's diagnosed with some kind of illness. (This could be a clue: there's an episode coming up with the title "The C Word" and the final episode's title has been released, it's called "Everyone Dies"). Or maybe he simply OD's on his Vicodin.
Fingers crossed they give the show a good enough ending and make up for the how boring the last 2 years have been.